Surender Singh Jadav Selected Research

Neoplasms (Cancer)

10/2023	Synthesis of aminomethyl linked (+)-usnic acid derivatives via the Mannich reaction and evaluation of their biological activities.
9/2023	AMPK targets a proto-oncogene TPD52 (isoform 3) expression and its interaction with LKB1 suppress AMPK-GSK3β signaling axis in prostate cancer.
6/2023	Synthetic and Medicinal Chemistry Approaches Toward WEE1 Kinase Inhibitors and Its Degraders.
1/2023	Synthesis of novel thiazoles bearing lupeol derivatives as potent anticancer and anti-inflammatory agents.
3/2019	Cink4T, a quinazolinone-based dual inhibitor of Cdk4 and tubulin polymerization, identified via ligand-based virtual screening, for efficient anticancer therapy.
1/2019	Novel Cellularly Active Inhibitor Regresses DDAH1 Induced Prostate Tumor Growth by Restraining Tumor Angiogenesis through Targeting DDAH1/ADMA/NOS Pathway.
1/2013	Synthesis, characterisation, and in vitro anticancer activity of curcumin analogues bearing pyrazole/pyrimidine ring targeting EGFR tyrosine kinase.

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Surender Singh Jadav Research Topics

Disease

7	Neoplasms (Cancer) 10/2023 - 01/2013
1	Prostatic Neoplasms (Prostate Cancer) 09/2023
1	Virus Diseases (Viral Diseases) 01/2023
1	Thrombocytopenia (Thrombopenia) 01/2023
1	Dengue (Dengue Fever) 01/2023
1	Lung Neoplasms (Lung Cancer) 09/2022
1	Colorectal Neoplasms (Colorectal Cancer) 02/2021
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 07/2020
1	Infections 11/2017
1	Edema (Dropsy) 01/2017
1	Ebola Hemorrhagic Fever 01/2015
1	Tuberculosis (Tuberculoses) 01/2015
1	Extensively Drug-Resistant Tuberculosis 01/2015

Drug/Important Bio-Agent (IBA)

2	Proteins (Proteins, Gene)FDA Link 09/2023 - 02/2021
2	Phosphotransferases (Kinase)IBA 09/2023 - 06/2023
2	LigandsIBA 01/2023 - 01/2015
2	VaccinesIBA 11/2017 - 01/2015
1	AntioxidantsIBA 10/2023
1	AminesIBA 10/2023
1	usnic acidIBA 10/2023
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 09/2023
1	Protein Isoforms (Isoforms)IBA 09/2023
1	OxazolesIBA 01/2023
1	lupeolIBA 01/2023
1	ThiazolesIBA 01/2023
1	Antiviral Agents (Antivirals)IBA 01/2023
1	HydrazonesIBA 01/2023
1	pyrazoleIBA 01/2023
1	eltrombopag FDA Link 01/2023
1	Antineoplastic Agents (Antineoplastics)IBA 09/2022
1	Carrier Proteins (Binding Protein)IBA 02/2021
1	CateninsIBA 02/2021
1	emopamil (levemopamil)IBA 02/2021
1	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 07/2020
1	TubulinIBA 03/2019
1	Cyclin-Dependent Kinase 4IBA 03/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019
1	CarrageenanIBA 01/2017
1	Antitubercular AgentsIBA 01/2015
1	CurcuminIBA 01/2013

Therapy/Procedure

2	Therapeutics 01/2023 - 01/2013
1	Drug Therapy (Chemotherapy) 01/2015